Therapeutic Target Details
| Target ID: | T45 |
| Target Name: | Insulin receptor substrate 1 |
| Synonyms: | Insulin receptor substrate 1; IRS-1 |
| GENE: | IRS1 |
| Action: | |
| Class: | Target is a single protein chain |
| UniProtKB ID: | P35568 |
| Entry Name: | IRS1_HUMAN |
| Related Drugs: | |
| Mechanism: | |
| Reference (PMIDs): |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B996524 | CHEMBL1572640 | Small molecule | 493.68 | C25H23N3O2S3 | NEUTRAL | Details | |
| B1075400 | CHEMBL1681823 | Small molecule | 467.66 | C22H33N3O4S2 | ACID | Details | |
| B1075401 | CHEMBL1685055 | Small molecule | 495.71 | C24H37N3O4S2 | NEUTRAL | Details | |
| B1075402 | CHEMBL1685056 | Small molecule | 481.68 | C23H35N3O4S2 | NEUTRAL | Details |
| Article ID | PMID | Source | Title |
|---|