Therapeutic Target Details
| Target ID: | T05 |
| Target Name: | Glucagon receptor |
| Synonyms: | Glucagon receptor; GL-R |
| GENE: | GCGR |
| Action: | AGONIST; ANTAGONIST; INHIBITOR |
| Class: | Target is a single protein chain |
| UniProtKB ID: | P47871 |
| Entry Name: | GCGR_HUMAN |
| Related Drugs: | Sar425899; Mk-0893; Pf-06291874; Mk-3577; Adomeglivant |
| Mechanism: | Glucagon receptor agonist; Glucagon receptor antagonist; Glucagon receptor inhibitor |
| Reference (PMIDs): | 12529935; 22708876; 25160589; 25656305; 26681715; 27111510; 27377054; 28371155; 28755409; 29283470; 29926478; 31608926; 33475255 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B000250 | CHEMBL10 | Small molecule | SB-203580 | 377.44 | C21H16FN3OS | NEUTRAL | Details |
| B019081 | CHEMBL278041 | Small molecule | SB-202190 | 331.35 | C20H14FN3O | NEUTRAL | Details |
| B019091 | CHEMBL276063 | Small molecule | 345.38 | C21H16FN3O | NEUTRAL | Details | |
| B019119 | CHEMBL17736 | Small molecule | 330.37 | C20H15FN4 | NEUTRAL | Details | |
| B019126 | CHEMBL17396 | Small molecule | 340.36 | C21H13FN4 | NEUTRAL | Details | |
| B019226 | CHEMBL17370 | Small molecule | 361.45 | C21H16FN3S | NEUTRAL | Details | |
| B019240 | CHEMBL416169 | Small molecule | 315.35 | C20H14FN3 | NEUTRAL | Details | |
| B019317 | CHEMBL17722 | Small molecule | 373.39 | C22H16FN3O2 | NEUTRAL | Details | |
| B032464 | CHEMBL24616 | Small molecule | 357.51 | C23H32FNO | NEUTRAL | Details | |
| B032700 | CHEMBL286555 | Small molecule | 375.5 | C23H31F2NO | NEUTRAL | Details |
| Article ID | PMID | Source | Title |
|---|