Therapeutic Target Details
| Target ID: | T08 |
| Target Name: | Alpha-galactosidase A |
| Synonyms: | Alpha-galactosidase A; Alpha-D-galactosidase A; Alpha-D-galactoside galactohydrolase; Galactosylgalactosylglucosylceramidase GLA; Melibiase; INN=Agalsidase; 3.2.1.22 |
| GENE: | GLA |
| Action: | STABILISER |
| Class: | Hydrolase |
| UniProtKB ID: | P06280 |
| Entry Name: | GLA_HUMAN |
| Related Drugs: | Migalastat; Migalastat Hydrochloride |
| Mechanism: | Alpha-galactosidase A stabiliser |
| Reference (PMIDs): |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B000097 | CHEMBL2 | Small molecule | PRAZOSIN | 383.41 | C19H21N5O4 | NEUTRAL | Details |
| B000690 | CHEMBL6703 | Small molecule | 175.19 | C10H9NO2 | NEUTRAL | Details | |
| B001620 | CHEMBL30 | Small molecule | CIMETIDINE | 252.35 | C10H16N6S | NEUTRAL | Details |
| B002580 | CHEMBL43 | Small molecule | AMSACRINE | 393.47 | C21H19N3O3S | NEUTRAL | Details |
| B002753 | CHEMBL268868 | Small molecule | DAPH | 329.36 | C20H15N3O2 | NEUTRAL | Details |
| B002866 | CHEMBL7917 | Small molecule | TYRPHOSTIN AG-1478 | 315.76 | C16H14ClN3O2 | NEUTRAL | Details |
| B003175 | CHEMBL414213 | Small molecule | 320.43 | C22H24O2 | NEUTRAL | Details | |
| B003838 | CHEMBL276727 | Small molecule | IODOACETAMIDE | 184.96 | C2H4INO | NEUTRAL | Details |
| B004485 | CHEMBL8565 | Small molecule | 350.36 | C14H14N4O5S | ACID | Details | |
| B004542 | CHEMBL418333 | Small molecule | 392.44 | C17H20N4O5S | ACID | Details |
| Article ID | PMID | Source | Title |
|---|