Clinical Trial Details
| Trial ID: | L1087 |
| Source ID: | NCT02827435 |
| Associated Drug: | Rocuronium Bromide |
| Title: | Acute Pharmacokinetic-pharmacodynamic Change of Rocuronium After Reperfusion of Renal Graft |
| Acronym: | |
| Status: | RECRUITING |
| Study Results: | NO |
| Results: | |
| Conditions: | End Stage Renal Disease|Transplantation |
| Interventions: | DRUG: Rocuronium bromide |
| Outcome Measures: | Primary: rocuronium plasma concentration (mcg/ml), PKPD modeling from measuring plasma rocuronium concentration and excreted urine rocuronium amount, 0, 1, 3, 5, 10, 30, 60, 90, 120 minutes after rocuronium second bolus injection|acceleromyography data (TOF ratio %), Muscle relaxation level (TOF, T1) will be evaluated via acceleromyography. The pharmacodynamic modeling with NONMEM throughout the kidney transplantation., intraoperative | |
| Sponsor/Collaborators: | Sponsor: Seoul National University Hospital |
| Gender: | ALL |
| Age: | ADULT |
| Phases: | |
| Enrollment: | 12 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE |
| Start Date: | 2016-07-01 |
| Completion Date: | 2024-12-31 |
| Results First Posted: | |
| Last Update Posted: | 2023-12-01 |
| Locations: | Seoul National University Hospital, Seoul, Korea, Republic of |
| URL: | https://clinicaltrials.gov/show/NCT02827435 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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