| Trial ID: | L1150 |
| Source ID: | NCT05807711
|
| Associated Drug: |
L-Methyl Folate And Methylcobalamine
|
| Title: |
Efficacy of L-methylfolate and Methylcobalamine in Treating Resistant Hypertension Associated with Elevated Serum Homocysteine in Hemodialysis Patients.
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
End Stage Renal Disease|Hypertension, Renal
|
| Interventions: |
DRUG: L-Methyl Folate and methylcobalamine
|
| Outcome Measures: |
Primary: average pre-dialysis blood pressure target of ≤ 140/90 mm Hg or an average post-dialysis blood pressure target of ≤ 130/80 mm Hg, To achieve an average pre-dialysis blood pressure target of ≤ 140/90 mm Hg or an average post-dialysis blood pressure target of ≤ 130/80 mm Hg. This should be parallel to lowering of serum homocysteine compared to baseline values, 3 months | Secondary: myocardial infarction, stroke and cardiovascular events., As a measurement of the prognosis patients will be followed up for the development of myocardial infarction, stroke and cardiovascular events for 3 months., 3 months
|
| Sponsor/Collaborators: |
Sponsor: Alexandria University
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
51
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2023-04-01
|
| Completion Date: |
2024-05-01
|
| Results First Posted: |
|
| Last Update Posted: |
2025-01-13
|
| Locations: |
Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt
|
| URL: |
https://clinicaltrials.gov/show/NCT05807711
|
