| Trial ID: | L1281 |
| Source ID: | NCT00532688
|
| Associated Drug: |
N-Acetylcysteine
|
| Title: |
N-Acetylcysteine in Heart Failure With Coexistent Chronic Renal Failure
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Heart Failure, Congestive|Kidney Failure, Chronic
|
| Interventions: |
DRUG: N-acetylcysteine
|
| Outcome Measures: |
Primary: Vascular function via non invasive ultrasound measured flow mediated dilatation, baseline, 4 weeks and 9 weeks|Estimated glomerular filtration rate calculated with Cockroft Gault equation., baseline, 4 weeks, 9 weeks | Secondary: Symptoms of heart failure, baseline, 4 weeks, 9 weeks|Death, baseline, 4 weeks, 9 weeks|Serum BNP (brain natriuretic peptide), baseline, 4 weeks, 9 weeks
|
| Sponsor/Collaborators: |
Sponsor: Bayside Health | Collaborators: The Alfred
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2|PHASE3
|
| Enrollment: |
10
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2007-09
|
| Completion Date: |
2008-02
|
| Results First Posted: |
|
| Last Update Posted: |
2007-09-20
|
| Locations: |
Alfred Hospital, Melbourne, Victoria, 3004, Australia
|
| URL: |
https://clinicaltrials.gov/show/NCT00532688
|
