| Outcome Measures: |
Primary: Circulating endothelial progenitor cells concentration and microparticles derived from endothelial cells, Effect of inhibiting xanthine oxidase with allopurinol in patients with CKD, Data collected after 4 weeks, 8 weeks and 12 weeks. | Secondary: Level of oxidative stress, Evaluated through quantification of oxygen-reactive species, After patient visit (0 weeks, 4, 8 and 12 weeks)|Level of micro inflammation, Evaluated through quantification of C-reactive protein, proinflammatory cytokines, CD14+ and CD16+ monocytes, After patient visit (0 weeks, 4, 8 and 12 weeks)|Level of endothelial dysfunction, Endothelium-dependant vasodilation in response to ischemia evaluated through changes in capillar flux using Doppler laser PeriFlux system 5000, After patient visit (0 weeks, 4, 8 and 12 weeks)|Blood pressure, Each visit (0 weeks, 4 weeks, 8 weeks and 12 weeks) for 24 hours|Glomerular filtration ratio, Estimated through MDRD-4 y Cockroft-Gault., After patient visit (0 weeks, 4 weeks, 8 weeks and 12 weeks)|Microalbuminuria / Proteinuria, Evaluated through albumin/creatinin ratio and protein/creatinine ratio, Daily, using first urine of the day as a sample.
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