| Trial ID: | L1661 |
| Source ID: | NCT00732069
|
| Associated Drug: |
Placebo
|
| Title: |
Study of Inflammation and Oxidative Stress in Persons Undergoing Dialysis
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT00732069/results
|
| Conditions: |
End Stage Renal Failure on Dialysis|Complication of Hemodialysis
|
| Interventions: |
DRUG: Placebo|DRUG: Ramipril|DRUG: Valsartan
|
| Outcome Measures: |
Primary: Interleukin 1 Beta, Mean difference in interleukin 1 beta concentration during treatment with ramipril versus treatment with placebo, During dialysis after one week of study drug | Secondary: F2-Isoprostanes, Mean difference in F2-isoprostanes during dialysis between treatment with ramipril or valsartan and placebo, During dialysis after one week of study drug
|
| Sponsor/Collaborators: |
Sponsor: Vanderbilt University | Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
19
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2008-08
|
| Completion Date: |
2011-12
|
| Results First Posted: |
2013-06-20
|
| Last Update Posted: |
2013-07-02
|
| Locations: |
Vanderbilt University Medical Center, Nashville, Tennessee, 37323, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT00732069
|
