Clinical Trial Details
| Trial ID: | L1872 |
| Source ID: | NCT03594591 |
| Associated Drug: | Antidiabetic Treatment By Usual Care |
| Title: | Changes in the Retinal and Carotid Microcirculation After Restoring Normoglycemia in Patients With Type 2 Diabetes |
| Acronym: | OCTAUS-T2D |
| Status: | UNKNOWN |
| Study Results: | NO |
| Results: | |
| Conditions: | Type 2 Diabetes Mellitus|Microangiopathy|Diabetic Retinopathy|Arteriosclerosis|Carotid Atherosclerosis |
| Interventions: | DRUG: Antidiabetic treatment by usual care |
| Outcome Measures: | Primary: Changes in retinal microcirculation (perifoveal vessel density), Changes in perifoveal vessel density, OCTA images will be processed to obtain vascular density measurements in this area (mm-1), 0, 1, 3 and 6 months|Changes in arterial wall microcirculation (vasa-vasorum density), Changes vasa-vasorum (VV) density, VV signal as the ratio of the contrast agent signal of the VV and that of the lumen of the artery, 0, 3 and 6 months | Secondary: Changes in retinal microcirculation (Parafoveal vessel density ), OCTA images will be processed to obtain vascular density measurements in this area (mm-1), 0, 1, 3 and 6 months|Changes in retinal microcirculation (Total Avascular Area ), OCTA images will be processed to obtain total avascular area measurements (mm2), 0, 1, 3 and 6 months|Changes in retinal microcirculation (Foveal Avascular Area), OCTA images will be processed to obtain foveal avascular zone area measurements (mm2), 0, 1, 3 and 6 months |
| Sponsor/Collaborators: | Sponsor: Hospital Clinic of Barcelona | Collaborators: Instituto de Salud Carlos III|Institut d'Investigacions Biomèdiques August Pi i Sunyer |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | |
| Enrollment: | 20 |
| Study Type: | OBSERVATIONAL |
| Study Designs: | Observational Model: |Time Perspective: p |
| Start Date: | 2018-01-02 |
| Completion Date: | 2020-01-01 |
| Results First Posted: | |
| Last Update Posted: | 2018-07-24 |
| Locations: | Hospital Clínic de Barcelona, Barcelona, 08036, Spain |
| URL: | https://clinicaltrials.gov/show/NCT03594591 |
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