Logo 1 Logo 2

Clinical Trial Details

Trial ID: L1874
Source ID: NCT02405260
Associated Drug: Ttp399 400 Mg
Title: Add Glucokinase Activator to Target A1c
Acronym: AGATA
Status: COMPLETED
Study Results: NO
Results:
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: TTP399 400 mg|DRUG: TTP399 800 mg|DRUG: Sitagliptin 100 mg|DRUG: Placebo
Outcome Measures: Primary: Change in HbA1c (Glycosylated haemoglobin), Day 1 to Day 168 | Secondary: HbA1c < 7% at 6 months, Day 1 to Day 168|HbA1c < 6.5% at 6 months, Day 1 to Day 168|Plasma Glucose Levels, Day 1 to Day 168|Lipid Levels, Day 1 to Day 168|Insulin Levels, Day 1 to Day 168|Lactate Levels, Day 1 to Day 168|C-peptide Levels, Day 1 to Day 168|Glucagon Levels, Day 1 to Day 168|Glucagon-like Peptide-1 Levels, Day 1 to Day 168|Change in Body Weight, Day 1 to Day 168|Adverse Events, Day 1 to Day 182|Blood Pressure, Day 1 to Day 182|Electrocardiogram Parameters, Day 1 to Day 182|Hematology, Day 1 to Day 182|Blood Chemistry, Day 1 to Day 182|Urinalysis, Day 1 to Day 182|Pulse, Day 1 to Day 182
Sponsor/Collaborators: Sponsor: vTv Therapeutics
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE2
Enrollment: 190
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Start Date: 2015-03
Completion Date: 2016-09
Results First Posted:
Last Update Posted: 2017-02-10
Locations: Mesa, Arizona, 85213, United States|Tuscon, Arizona, 85741, United States|Canoga Park, California, 91303, United States|Huntington Park, California, 90255, United States|Los Angeles, California, 90056, United States|West Hills, California, 91307, United States|Centennial, Colorado, 80112, United States|Littleton, Colorado, 80127, United States|Waterbury, Connecticut, 06708, United States|West Palm Beach, Florida, 33409, United States|Gurnee, Illinois, 60031, United States|Evansville, Indiana, 47725, United States|Rochester, Minnesota, 55905, United States|Greensboro, North Carolina, 27408, United States|Moncks Corner, South Carolina, 29461, United States|San Antonio, Texas, 78209, United States|San Antonio, Texas, 78229, United States|Schertz, Texas, 78154, United States|Norfolk, Virginia, 23507, United States|Richland, Washington, 99352, United States
URL: https://clinicaltrials.gov/show/NCT02405260

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress