| Trial ID: | L1887 |
| Source ID: | NCT01088594
|
| Associated Drug: |
Pioglitazone/Rosiglitazone/Placebo
|
| Title: |
A Methodological Study To Evaluate The Effects of Single Oral Doses Of Pioglitazone 45 mg And Rosiglitazone 8 mg On Sodium Balance In Healthy Male Volunteers
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: pioglitazone/rosiglitazone/placebo|DRUG: rosiglitazone/pioglitazone/placebo|DRUG: placebo/pioglitazone/rosiglitazone|DRUG: pioglitazone/placebo/rosiglitazone|DRUG: rosiglitazone/placebo/pioglitazone|DRUG: placebo/rosiglitazone/pioglitazone
|
| Outcome Measures: |
Primary: Time-course urinary sodium excretion calculated on the Day 1 of each study period, 0-6 hours|Time-course absolute urinary sodium excretion calculated on the Day 1 of each study period, 0-6 hours | Secondary: Sodium clearance on Day 1 of each study period, 0-6 hours|Creatinine clearance calculated on Day 1 of each study period, 0-6 hours
|
| Sponsor/Collaborators: |
Sponsor: Solvay Pharmaceuticals
|
| Gender: |
MALE
|
| Age: |
ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
12
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
|
| Start Date: |
2010-02
|
| Completion Date: |
2010-03
|
| Results First Posted: |
|
| Last Update Posted: |
2010-03-17
|
| Locations: |
S337.1.004 Site #, London, United Kingdom
|
| URL: |
https://clinicaltrials.gov/show/NCT01088594
|
