| Trial ID: | L2045 |
| Source ID: | NCT02009527
|
| Associated Drug: |
N-Hydroxy-Nor-Arginine
|
| Title: |
Arginase Inhibition in Ischemia-reperfusion Injury
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Coronary Artery Disease|Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: N-hydroxy-nor-arginine|DRUG: NaCl
|
| Outcome Measures: |
Primary: Change in endothelial function, Flow-mediated dilatation of the radial artery, 20 min of reperfusion |
|
| Sponsor/Collaborators: |
Sponsor: Karolinska Institutet
|
| Gender: |
MALE
|
| Age: |
CHILD, ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
24
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2012-01
|
| Completion Date: |
2013-09
|
| Results First Posted: |
|
| Last Update Posted: |
2015-04-20
|
| Locations: |
Karolinska Institutet, Stockholm, 17176, Sweden
|
| URL: |
https://clinicaltrials.gov/show/NCT02009527
|
