| Trial ID: | L2158 |
| Source ID: | NCT01135394
|
| Associated Drug: |
Pioglitazone
|
| Title: |
Pharmacogenomics of Thiazolidinediones
|
| Acronym: |
PPAR
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01135394/results
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: Pioglitazone
|
| Outcome Measures: |
Primary: Change in Insulin Resistance, Change in insulin resistance was calculated as change (end of treatment minus baseline) in HOMA-IR index (glucose (mg/dL) x insulin (μU/mL)/405), 12 weeks | Secondary: Number of Genes Determined to be Correlated With Change in Insulin Sensitivity, Number of genes determined to be correlated with change in insulin sensitivity as determined by HOMA-IR with a p-value below 0.000001, 12 weeks
|
| Sponsor/Collaborators: |
Sponsor: University of Maryland, Baltimore | Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
|
| Enrollment: |
114
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2009-03
|
| Completion Date: |
2018-05-31
|
| Results First Posted: |
2021-05-18
|
| Last Update Posted: |
2024-03-15
|
| Locations: |
University of Maryland School of Medicine, Baltimore, Maryland, 21201, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01135394
|
