| Trial ID: | L2185 |
| Source ID: | NCT00519727
|
| Associated Drug: |
Isis 325568
|
| Title: |
Safety Study of ISIS 325568 in Healthy Volunteers
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: ISIS 325568
|
| Outcome Measures: |
Primary: safety and tolerability, 30 days for single dose, 16 weeks for multi-dose | Secondary: Pharmacokinetic profile all doses and Pharmacodynamics for multi-dose groups., 4 days for single dose, 16 weeks for multi-dose
|
| Sponsor/Collaborators: |
Sponsor: Ionis Pharmaceuticals, Inc.
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
60
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2007-08
|
| Completion Date: |
2008-06
|
| Results First Posted: |
|
| Last Update Posted: |
2008-08-19
|
| Locations: |
Centre for Human Drug Research, Leiden, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT00519727
|
