| Outcome Measures: |
Primary: plasma renin concentration, 6 weeks | Secondary: Urinary albumin excretion, 6 weeks|GFR, 6 weeks|Fractional excretion of sodium, 6 weeks|Urinary excretion of aquaporin-2, 6 weeks|Urinary excretion of ENaC-beta, 6 weeks|Urinary excretion of NCC, 6 weeks|Plasma concentration of aldosterone, 6 weeks|Plasma concentration of angiotensin-II, 6 weeks|Plasma concentration of ADH, 6 weeks|Plasma concentration of atrial natriuretic peptide, 6 weeks|Plasma concentration of brain natriuretic peptide, 6 weeks|Plasma concentration of endothelin, 6 weeks|24-hr ambulatory blood pressure, 6 weeks|Central blood pressure, 6 weeks|Pulse wave velocity, 6 weeks|augmentation index, 6 weeks|Plasma concentration of ionized calcium, 6 weeks|Plasma concentration of phosphate, 6 weeks|Plasma concentration of alkaline phosphatase, 6 weeks|Plasma concentration of Parathyroid hormon, 6 weeks|Plasma concentration of 25-hydroxy-vitamin D, 6 weeks|Plasma concentration of ultrasensitive CRP, 6 weeks|Plasma concentration of TNF-alpha, 6 weeks|Plasma concentration of TGF-beta, 6 weeks|Urinary excretion of calcium, 6 weeks|Plasma concentration of ADMA, 6 weeks
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