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Clinical Trial Details

Trial ID: L2293
Source ID: NCT01881074
Associated Drug: Triclosan Containing Toothpaste
Title: Periodontal Treatment Response in Type II Diabetic Patients
Acronym:
Status: COMPLETED
Study Results: NO
Results:
Conditions: Type II Diabetes|Periodontal Disease
Interventions: DRUG: Triclosan containing toothpaste|DRUG: Non-triclosan containing toothpaste
Outcome Measures: Primary: Clinical Periodontal Parameters, The changes in clinical parameters(i.e. pocket depth, plaque, clinical attachment loss) during periodontal treatment from baseline to 3 months, 6 months and 12 months. Clinical parameters will be assessed using a conventional periodontal probe and recorded in supporting software (Florida Probe)., Baseline, 3, 6 and 12 months|Local Inflammatory Markers, The changes in local inflammatory markers (i.e. cytokines, chemokines, metalloproteinases) during periodontal treatment from baseline to 3 months, 6 months and 12 months. Local inflammatory markers in gingival crevicular fluid will be assayed in the laboratory., Baseline, 3, 6 and 12 months | Secondary: Glycemic Control, The changes in glycemic control (i.e. HbA1C levels) during periodontal treatment from baseline to 3 months, 6 months and 12 months. Blood will be analyzed by the core lab facility at the University of Florida and Shands hospital and in the clinic/laboratory using a commercially available finger prick device and testing strips., Baseline, 3, 6 and 12 months|Systemic Inflammatory Markers, The changes in systemic inflammatory markers (i.e. cytokines, chemokines, metalloproteinases) during periodontal treatment from baseline to 3 months, 6 months and 12 months of periodontal treatment. Inflammatory markers in venous blood will be assayed in the laboratory., Baseline, 3, 6 and 12 months
Sponsor/Collaborators: Sponsor: University of Florida | Collaborators: Colgate Palmolive
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases:
Enrollment: 74
Study Type: OBSERVATIONAL
Study Designs: Observational Model: |Time Perspective: p
Start Date: 2012-06
Completion Date: 2015-12
Results First Posted:
Last Update Posted: 2018-09-17
Locations: University of Florida, Gainesville, Florida, 32610, United States
URL: https://clinicaltrials.gov/show/NCT01881074