| Outcome Measures: |
Primary: Area under the semaglutide milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,sema,D10,milk), nmol\*h/L, From 0 to 24 hours after the 10th dosing (day 10)|Area under the salcaprozate sodium (SNAC) milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,SNAC,D10,milk), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10) | Secondary: Average semaglutide milk concentration during a dosing interval after the 10th dosing (Cavg,sema,D10,milk), nmol/L, From 0 to 24 hours after the 10th dosing (day 10)|Maximum semaglutide milk concentration during a dosing interval after the 10th dosing (Cmax,sema,D10,milk), nmol/L, From 0 to 24 hours after the 10th dosing (day 10)|Minimum semaglutide milk concentration during a dosing interval after the 10th dosing (Cmin,sema,D10,milk), nmol/L, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum semaglutide milk concentration during a dosing interval after the 10th dosing (tmax,sema,D10,milk), Hours, From 0 to 24 hours after the 10th dosing (day 10)|Estimated daily infant semaglutide dose, mg/kg/day, From 0 to 24 hours after the 10th dosing (day 10)|Relative daily infant semaglutide dose, From 0 to 24 hours after the 10th dosing (day 10)|Average SNAC milk concentration during a dosing interval after the 10th dosing (Cavg,SNAC,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC milk concentration during a dosing interval after the 10th dosing (Cmax,SNAC,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Minimum SNAC milk concentration during a dosing interval after the 10th dosing (Cmin,SNAC,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC milk concentration during a dosing interval after the 10th dosing (tmax,SNAC,D10,milk), hours, From 0 to 24 hours after the 10th dosing (day 10)|Estimated daily infant SNAC dose, ng/kg/day, From 0 to 24 hours after the 10th dosing (day 10)|Relative daily infant SNAC dose, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E494 milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E494,D10,milk), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Average SNAC metabolite E494 milk concentration during a dosing interval after the 10th dosing (Cavg,E494,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E494 milk concentration during a dosing interval after the 10th dosing (Cmax,E494,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Minimum SNAC metabolite E494 milk concentration during a dosing interval after the 10th dosing (Cmin,E494,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E494 milk concentration after the 10th dosing (tmax,E494,D10,milk), hours, From 0 to 24 hours after the 10th dosing (day 10)|Estimated daily infant SNAC metabolite E494 dose, ng/kg/day, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E506 milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E506,D10,milk), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Average SNAC metabolite E506 milk concentration during a dosing interval after the 10th dosing (Cavg,E506,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E506 milk concentration during a dosing interval after the 10th dosing (Cmax,E506,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Minimum SNAC metabolite E506 milk concentration during a dosing interval after the 10th dosing (Cmin,E506,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E506 milk concentration after the 10th dosing (tmax,E506,D10,milk), hours, From 0 to 24 hours after the 10th dosing (day 10)|Estimated daily infant SNAC metabolite E506 dose, ng/kg/day, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E1245 milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E1245,D10,milk), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Average SNAC metabolite E1245 milk concentration during a dosing interval after the 10th dosing (Cavg,E1245,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E1245 milk concentration during a dosing interval after the 10th dosing (Cmax,E1245,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Minimum SNAC metabolite E1245 milk concentration during a dosing interval after the 10th dosing (Cmin,E1245,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E1245 milk concentration after the 10th dosing (tmax,E1245,D10,milk), hours, From 0 to 24 hours after the 10th dosing (day 10)|Estimated daily infant SNAC metabolite E1245 dose, ng/kg/day, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E1246 milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E1246,D10,milk), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Average SNAC metabolite E1246 milk concentration during a dosing interval after the 10th dosing (Cavg,E1246,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E1246 milk concentration during a dosing interval after the 10th dosing (Cmax,E1246,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Minimum SNAC metabolite E1246 milk concentration during a dosing interval after the 10th dosing (Cmin,E1246,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E1246 milk concentration in milk after the 10th dosing (tmax,E1246,D10,milk), hours, From 0 to 24 hours after the 10th dosing (day 10)|Estimated daily infant SNAC metabolite E1246 dose, ng/kg/day, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E1247 milk concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E1247,D10,milk), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Average SNAC metabolite E1247 milk concentration during a dosing interval after the 10th dosing (Cavg,E1247,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E1247 milk concentration during a dosing interval after the 10th dosing (Cmax,E1247,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Minimum SNAC metabolite E1247 milk concentration during a dosing interval after the 10th dosing (Cmin,E1247,D10,milk), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E1247 milk concentration after the 10th dosing (tmax,E1247,D10,milk), hours, From 0 to 24 hours after the 10th dosing (day 10)|Estimated daily infant SNAC metabolite E1247 dose, ng/kg/day, From 0 to 24 hours after the 10th dosing (day 10)|Area under the semaglutide plasma concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,sema,D10,plasma), nmol\*h/L, From 0 to 24 hours after the 10th dosing (day 10)|Maximum semaglutide plasma concentration during a dosing interval after the 10th dosing (Cmax,sema,D10,plasma), nmol/L, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum semaglutide plasma concentration during a dosing interval after the 10th dosing (tmax,sema,D10,plasma), hours, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC plasma concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,SNAC,D10,plasma), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC plasma concentration during a dosing interval after the 10th dosing (Cmax,SNAC,D10,plasma), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC plasma concentration during a dosing interval after the 10th dosing (tmax,SNAC,D10,plasma), hours, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E494 plasma concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E494,D10,plasma), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E494 plasma concentration during a dosing interval after the 10th dosing (Cmax,E494,D10,plasma), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E494 plasma concentration during a dosing interval after the 10th dosing (tmax,E494,D10,plasma), hours, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E506 plasma concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E506,D10,plasma), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E506 plasma concentration during a dosing interval after the 10th dosing (Cmax,E506,D10,plasma), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E506 plasma concentration during a dosing interval after the 10th dosing (tmax,E506,D10,plasma), hours, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E1245 plasma concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E1245,D10,plasma), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E1245 plasma concentration during a dosing interval after the 10th dosing (Cmax,E1245,D10,plasma), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E1245 plasma concentration during a dosing interval after the 10th dosing (tmax,E1245,D10,plasma), hours, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E1246 plasma concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E1246,D10,plasma), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E1246 plasma concentration during a dosing interval after the 10th dosing (Cmax,E1246,D10,plasma), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E1246 plasma concentration during a dosing interval after the 10th dosing (tmax,E1246,D10,plasma), hours, From 0 to 24 hours after the 10th dosing (day 10)|Area under the SNAC metabolite E1247 plasma concentration-time curve during a dosing interval after the 10th dosing (AUC0-24h,E1247,D10,plasma), ng\*h/mL, From 0 to 24 hours after the 10th dosing (day 10)|Maximum SNAC metabolite E1247 plasma concentration during a dosing interval after the 10th dosing (Cmax,E1247,D10,plasma), ng/mL, From 0 to 24 hours after the 10th dosing (day 10)|Time to maximum SNAC metabolite E1247 plasma concentration during a dosing interval after the 10th dosing (tmax,E1247,D10,plasma), hours, From 0 to 24 hours after the 10th dosing (day 10)
|
