| Trial ID: | L0272 |
| Source ID: | NCT03223883
|
| Associated Drug: |
Curcumin
|
| Title: |
Curcumin and Vascular and Cognitive Function in Patients With Chronic Kidney Disease
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT03223883/results
|
| Conditions: |
Chronic Kidney Diseases|Cognitive Decline
|
| Interventions: |
DRUG: Curcumin|OTHER: Placebo
|
| Outcome Measures: |
Primary: Change in Vascular Endothelial Function at 12 Months, Brachial artery flow-mediated dilation, changed in diameter in brachial artery in response to shear stress, 12 months | Secondary: Large Artery Stiffness, Aortic pulse wave velocity, 12 months|Cognitive Function, NIH toolbox battery- Executive Function Age-Corrected Standard Score is reported (T-score): This score compares the score of the test-taker to those in the NIH Toolbox nationally representative normative sample at the same age, where a score of 100 indicates performance that was at the national average for the test-taking participant's age. Age-corrected standard scores were derived separately for children (ages 3-17) and adults (ages 18-85). A score of 115 or 85, for example, would indicate that the participant's performance is 1 SD above or below the national average, respectively, when compared with like-aged participants. Higher scores indicate better performance., 12 months
|
| Sponsor/Collaborators: |
Sponsor: Diana Jalal | Collaborators: University of Colorado, Boulder|Stanford University|University of Colorado, Denver
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
94
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2018-06-01
|
| Completion Date: |
2023-01-25
|
| Results First Posted: |
2024-10-08
|
| Last Update Posted: |
2024-10-08
|
| Locations: |
University of Iowa, Iowa City, Iowa, 52242, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT03223883
|
