| Trial ID: | L2974 |
| Source ID: | NCT00823680
|
| Associated Drug: |
Placebo
|
| Title: |
A Study of RO5093151 and RO5027838 in Patients With Type 2 Diabetes Mellitus on a Stable Dose of Metformin
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus Type 2
|
| Interventions: |
DRUG: Placebo|DRUG: RO5027838|DRUG: RO5027838|DRUG: RO5093151|DRUG: RO5093151
|
| Outcome Measures: |
Primary: Absolute change in mean daily plasma glucose, From baseline to day 27 | Secondary: Fasting plasma glucose, Baseline, and weeks 1, 2, 3 and 4|Post-prandial glucose and insulin, Baseline, weeks 2 and 4|Insulin sensitivity, beta cell function, lipid profile, HbA1C, At baseline, and at planned visits up to week 4|Adverse events, lab parameters, vital signs, body weight, At baseline, and at planned visits up to week 4
|
| Sponsor/Collaborators: |
Sponsor: Hoffmann-La Roche
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
110
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2009-04
|
| Completion Date: |
2009-08
|
| Results First Posted: |
|
| Last Update Posted: |
2016-07-28
|
| Locations: |
Chula Vista, California, 91911, United States|Miami, Florida, 330014, United States|Graz, 8036, Austria|München, 80636, Germany|Neuss, 41460, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT00823680
|
