| Trial ID: | L3064 |
| Source ID: | NCT00766857
|
| Associated Drug: |
Exenatide
|
| Title: |
Effects of Exenatide in Type 2 Diabetic Patients With Congestive Heart Failure
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus|Congestive Heart Failure
|
| Interventions: |
DRUG: exenatide|DRUG: Insulin glargine
|
| Outcome Measures: |
Primary: Cardiac Magnetic Resonance (CMR) will be used to assess global cardiac function (LV ejection fraction)., week -2 and week 11 | Secondary: Cardiac oxygen consumption, cardiac efficiency and stress perfusion will be assessed by Positron Emission Tomography (PET) using 11C-acetate and H2-15O, week -2 and week 26|Cardiac function, dimensions and scarring will be measured bij CMR, week -2 and week 26|Myocardial diastolic function parameters will be obtained bij trans thoracal echocardiography. Comparisons will be made of strain and torsion measures obtained bij CMR and echocardiography., week -2 and week 26|Exercise capacity and performance will be assessed by a 6-minute walking test, week -1 and week 27
|
| Sponsor/Collaborators: |
Sponsor: Amsterdam UMC, location VUmc
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
27
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2009-05
|
| Completion Date: |
2012-12
|
| Results First Posted: |
|
| Last Update Posted: |
2015-12-09
|
| Locations: |
VU University Medical Center, Amsterdam, Noord-Holland, 1081, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT00766857
|
