| Trial ID: | L3705 |
| Source ID: | NCT01626469
|
| Associated Drug: |
Captopril
|
| Title: |
Measurement of Eye Blood Flow and Renal Function in Healthy and Diabetic Patients
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Captopril|DRUG: placebo
|
| Outcome Measures: |
Primary: Change in ophthalmic artery blood flow from baseline, Eye blood flow will be measured at baseline and post drug time points (3 total), 1 hour post drug, 2 hours post drug, 3 hours post drug | Secondary: Change in blood pressure from baseline, Blood pressure will be monitored throughout the study starting at baseline, Every 15 minutes for 3 hours|Change in renal plasma flow (RPF) from baseline, Renal Plasma Flow (to measure kidney function) will be measured at baseline and post drug time points (3 total), 1 hour post drug, 2 hours post drug, 3 hours post drug
|
| Sponsor/Collaborators: |
Sponsor: Brigham and Women's Hospital
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1|PHASE2
|
| Enrollment: |
24
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2012-05
|
| Completion Date: |
2020-09
|
| Results First Posted: |
|
| Last Update Posted: |
2019-08-01
|
| Locations: |
Brigham and Women's Hospital, Boston, Massachusetts, 02115, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01626469
|
