| Trial ID: | L3979 |
| Source ID: | NCT01983046
|
| Associated Drug: |
Three Different Mixture Of Acetate, Butyrate And Propionate And Palcebo
|
| Title: |
Rectal Short Chain Fatty Acids Combinations and Substrate and Energy Metabolism
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Obesity|Type 2 Diabetes
|
| Interventions: |
DRUG: Three different mixture of acetate, butyrate and propionate and palcebo
|
| Outcome Measures: |
Primary: fat oxidation, we will measure fat oxidation and energy expenditure by using the ventilated hood system, 4 hours total (2 hours fasting, 2 hours postprandial) | Secondary: Hormones that influence energy metabolism, 4 hours total (2 hours fasting and 2 hours postprandial)|Circulating metabolites, 4 hours total (2 hours fasting and 2 hours postprandial)|Hormones that influence energy metabolism - Circulating metabolites - Inflammatory markers - plasma SCFA content; - Indirect markers of insulin sensitivity - Appetite (VAS-scoring)., 4 hours total (2 hours fasting and 2 hours postprandial)
|
| Sponsor/Collaborators: |
Sponsor: Maastricht University Medical Center | Collaborators: Top Institute Food and Nutrition
|
| Gender: |
MALE
|
| Age: |
ADULT
|
| Phases: |
|
| Enrollment: |
12
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
|
| Start Date: |
2013-09
|
| Completion Date: |
2014-02
|
| Results First Posted: |
|
| Last Update Posted: |
2014-10-21
|
| Locations: |
University Maastricht, Maastricht, Limburg, 6229 ER, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT01983046
|
