| Trial ID: | L4000 |
| Source ID: | NCT02773381
|
| Associated Drug: |
Semaglutide
|
| Title: |
A Trial Investigating the Effect of Oral Semaglutide Compared With Placebo on Postprandial Glucose and Triglyceride Metabolism, Energy Intake, Appetite Sensations and Gastric Emptying in Subjects With Type 2 Diabetes
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes|Diabetes Mellitus, Type 2
|
| Interventions: |
DRUG: semaglutide|DRUG: placebo
|
| Outcome Measures: |
Primary: Area under the serum glucose concentration-time curve, At 12 weeks of treatment | Secondary: Ad libitum energy intake during a lunch meal (following a standardised breakfast meal), At 12 weeks of treatment|Mean postprandial increase in serum glucose concentration, At 12 weeks of treatment|Mean postprandial increase in TG (triglycerides) concentration, At 12 weeks of treatment|Area under the paracetamol plasma concentration-time curve, At 12 weeks of treatment
|
| Sponsor/Collaborators: |
Sponsor: Novo Nordisk A/S
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
15
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2016-06-02
|
| Completion Date: |
2018-10-19
|
| Results First Posted: |
|
| Last Update Posted: |
2020-12-08
|
| Locations: |
Novo Nordisk Investigational Site, Leeds, LS2 9LH, United Kingdom
|
| URL: |
https://clinicaltrials.gov/show/NCT02773381
|
