| Trial ID: | L4071 |
| Source ID: | NCT01858896
|
| Associated Drug: |
Glucagon-Like Peptide- 1 (Glp-1) Infusion
|
| Title: |
GLP-1 and Hypoglycemia
|
| Acronym: |
|
| Status: |
ACTIVE_NOT_RECRUITING
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Glucagon-Like Peptide- 1 (GLP-1) infusion|OTHER: Placebo Comparator: Saline Infusion
|
| Outcome Measures: |
Primary: Change in Plasminogen Activation inhibitor-1 (PAi-1), measurements of change in PAi-1 at baseline and during the end of the glucose clamp period (2 hours), change from baseline to end of clamp period|Change in Flow mediated dilation (FMD), flow mediated dilation of the brachial artery will be measured for change from baseline and end of glucose clamp (\~4 hours), change from baseline and end of clamp |
|
| Sponsor/Collaborators: |
Sponsor: University of Maryland, Baltimore
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
EARLY_PHASE1
|
| Enrollment: |
28
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
|
| Start Date: |
2013-07
|
| Completion Date: |
2026-02
|
| Results First Posted: |
|
| Last Update Posted: |
2024-09-05
|
| Locations: |
University of Maryland, Baltimore, Baltimore, Maryland, 21201, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01858896
|
