Clinical Trial Details
| Trial ID: | L4258 |
| Source ID: | NCT00460941 |
| Associated Drug: | Placebo |
| Title: | A Titration Study of a Glucagon-Like Peptide-1 (GLP-1) Analogue in Patients With Type 2 Diabetes Treated With Metformin. |
| Acronym: | |
| Status: | COMPLETED |
| Study Results: | NO |
| Results: | |
| Conditions: | Diabetes Mellitus Type 2 |
| Interventions: | DRUG: Placebo|DRUG: Taspoglutide 20mg|DRUG: Taspoglutide 20mg-30mg|DRUG: Taspoglutide 20mg-40mg |
| Outcome Measures: | Primary: Percentage of patients withdrawn because of gastrointestinal effects, Week 9 | Secondary: Mean changes in 24h blood glucose Area Under the Curve (AUC), Fasting Plasma Glucose (FPG), fructosamine, Hemoglobin A1c (HbA1c), body weight, Adverse Events (AEs), laboratory parameters., Week 9 |
| Sponsor/Collaborators: | Sponsor: Hoffmann-La Roche |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | PHASE2 |
| Enrollment: | 133 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT |
| Start Date: | 2007-04 |
| Completion Date: | 2008-01 |
| Results First Posted: | |
| Last Update Posted: | 2016-11-02 |
| Locations: | Harrisburg, Arkansas, 72432, United States|Hot Springs, Arkansas, 71913, United States|Jonesboro, Arkansas, 72401, United States|National City, California, 91950, United States|Jacksonville, Florida, 32216, United States|Madisonville, Kentucky, 42431, United States|Hyattsville, Maryland, 20783, United States|Winston-salem, North Carolina, 27103, United States|Dallas, Texas, 75230, United States|Dallas, Texas, 75231, United States|Richmond, Virginia, 23294, United States|Adelaide, 5000, Australia|Camperdown, 2050, Australia|Besancon, 25030, France|Corbeil Essonnes, 91106, France|Narbonne, 11108, France|Paris, 75877, France|Poitiers, 86021, France|Berlin, 10115, Germany|München, 80636, Germany|Neuss, 41460, Germany|Chihuahua, 31238, Mexico|Culiacan, 80020, Mexico|Monterrey, 64410, Mexico|Tampico, 89109, Mexico|Lima, 10, Peru|Lima, 31, Peru|Lima, LIMA 29, Peru|Ponce, 00716, Puerto Rico |
| URL: | https://clinicaltrials.gov/show/NCT00460941 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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