| Trial ID: | L0456 |
| Source ID: | NCT00356265
|
| Associated Drug: |
Procedure: Regional Phenylephrine Arterial Infusion
|
| Title: |
Alpha-Adrenoceptor Vascular Function In Chronic Kidney Disease Focus On The Role Of Endothelial Nitric Oxide
|
| Acronym: |
|
| Status: |
TERMINATED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT00356265/results
|
| Conditions: |
Chronic Kidney Disease|Hypertension
|
| Interventions: |
DRUG: Procedure: Regional phenylephrine arterial infusion
|
| Outcome Measures: |
Primary: α1-adrenoceptor Vasoreactivity With L-NMMA, Vasoreactivity is defined as Forearm blood flow, dose response curve; ml per minute per log of phenylephrine, or FABF ml/min/logPE; The x axis is the ml/min value and the y axis is the log Phenylephrine concentration., up to 8 hours|α1-adrenoceptor Vasoreactivity With Endogenous ADMA, up to 8 hours |
|
| Sponsor/Collaborators: |
Sponsor: University of Michigan | Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
|
| Enrollment: |
18
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
|
| Start Date: |
2006-07
|
| Completion Date: |
2010-11
|
| Results First Posted: |
2018-01-23
|
| Last Update Posted: |
2018-01-23
|
| Locations: |
University of Michigan Hospital, Ann Arbor, Michigan, 48109, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT00356265
|
