| Trial ID: | L0459 |
| Source ID: | NCT06203236
|
| Associated Drug: |
Furosemide 20 Mg
|
| Title: |
Natriuresis-Guided Diuretic Therapy in Patients With Acute Heart Failure With Reduced Ejection Fraction and Chronic Kidney Disease
|
| Acronym: |
|
| Status: |
NOT_YET_RECRUITING
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Acute Heart Failure|Chronic Kidney Diseases
|
| Interventions: |
DRUG: Furosemide 20 MG|OTHER: diuretic therapy
|
| Outcome Measures: |
Primary: Mean total sodium in urine in both groups., 24 hours|Duration of the index hospitalization in both groups., 24 hours | Secondary: All-cause mortality or HF rehospitalization in both groups., 90 days|Mean total sodium in urine in both groups., 90 days|Incidence of arrythmatic complications as AF, VT and incidence of hypokalemia and hypomagnesaemia in both groups., 90 days|Mean total urine output in both groups., 90 days
|
| Sponsor/Collaborators: |
Sponsor: Assiut University
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
300
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2024-01
|
| Completion Date: |
2025-11
|
| Results First Posted: |
|
| Last Update Posted: |
2024-01-12
|
| Locations: |
|
| URL: |
https://clinicaltrials.gov/show/NCT06203236
|
