| Outcome Measures: |
Primary: Serious Adverse Events, Number of serious adverse events (SAEs) per treatment, From first dose until follow-up call, up to 7 weeks per subject | Secondary: Glucagon Cmax (Fasting), Pharmacokinetic parameter: Maximum concentration of glucagon, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, 120 and 180 minutes post-injection|Glucagon Cmax (Post-insulin), Pharmacokinetic parameter: Maximum concentration of glucagon, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection|Glucagon Area Under the Curve (AUC) (Fasting), Pharmacokinetic parameter: Area under the glucagon concentration curve from 0 to 120 minutes, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection|Glucagon AUC (Post-insulin), Pharmacokinetic parameter: Area under the glucagon concentration curve from 0 to 120 minutes, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection|Glucagon Tmax (Fasting), Pharmacokinetic parameter: Time to reach maximum concentration of glucagon, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, 120 and 180 minutes post-injection|Glucagon Tmax (Post-insulin), Pharmacokinetic parameter: Time to reach maximum concentration of glucagon, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection|Glucose Cmax (Fasting), Pharmacodynamic parameter: Maximum concentration of glucose, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, 120 and 180 minutes post-injection|Glucose Cmax (Post-insulin), Pharmacodynamic parameter: Maximum concentration of glucose, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection|Glucose AUC (Fasting), Pharmacodynamic parameter: baseline adjusted area under the glucagon concentration curve from 0 to 120 minutes, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection|Glucose AUC (Post-insulin), Pharmacodynamic parameter: baseline adjusted area under the glucose concentration curve from 0-120 minutes, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection|Glucose Tmax (Fasting), Pharmacodynamic parameter: Time to reach maximum concentration of glucose, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, 120 and 180 minutes post-injection|Glucose Tmax (Post-insulin), Pharmacodynamic parameter: Time to reach maximum concentration of glucose, Approximately 15 and 0 minutes before each injection and at 5, 10, 15, 20, 30, 45, 60, and 120 minutes post-injection
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