| Outcome Measures: |
Primary: Temporal lobe volume in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Voxel-based morphometry via Sagittal 3D Accelerated MPRAGE/IRSPGR, Baseline|Temporal lobe cortical thickness in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Voxel-based morphometry via Sagittal 3D Accelerated MPRAGE/IRSPGR, Baseline|Whole brain white matter hyperintensities volume in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Structural cerebrovascular disease via Sagittal 3D FLAIR, Baseline|Regional homogeneity of the default mode network in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Resting-state functional connectivity via Axial T2\* EPI fcMRI, Baseline|Whole brain cerebral blood flow in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Cerebral blood flow or perfusion via Axial 3D pCASL, Baseline|Whole brain fractional anisotropy in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Gray matter and white matter microstructure via Diffusion Kurtosis Imaging, Baseline|Standardized uptake value ratio for hippocampal to cerebellar comparison in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Tau accumulation via positron emission tomography with PI-2620 radiotracer, Baseline|Standardized uptake value ratio for entorhinal to cerebellar comparison in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Tau accumulation via positron emission tomography with PI-2620 radiotracer, Baseline|Standardized uptake value ratio for cerebral to cerebellar comparison in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Tau accumulation via positron emission tomography with PI-2620 radiotracer, Baseline | Secondary: Whole brain gray matter volume in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Voxel-based morphometry via Sagittal 3D Accelerated MPRAGE/IRSPGR, Baseline|Whole brain white matter volume in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Voxel-based morphometry via Sagittal 3D Accelerated MPRAGE/IRSPGR, Baseline|Perivascular space in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Structural cerebrovascular disease via Sagittal 3D FLAIR, Baseline|Atlas based region of interest cerebral blood flow in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Cerebral blood flow via Axial 3D pCASL, Baseline|Atlas based region of interest fractional anisotropy in young adults with Type 1 diabetes, Type 2 diabetes, and young adults without diabetes, Gray matter and white matter microstructure via Diffusion Kurtosis Imaging, Baseline
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