| Trial ID: | L5049 |
| Source ID: | NCT05473364
|
| Associated Drug: |
Acetazolamide
|
| Title: |
Acetazolamide in Persons with Type 1 Diabetes
|
| Acronym: |
|
| Status: |
RECRUITING
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 1 Diabetes
|
| Interventions: |
DRUG: Acetazolamide
|
| Outcome Measures: |
Primary: Change in mGFR percent, The change in mGFR percent from pre-dosing to post-treatment as measured by the iohexol procedure., 2 Weeks|Preservation of Serum Bicarbonate, The preservation of serum bicarbonate concentrations at ≥ 22 meq/L from pre-dosing to post treatment., 2 Weeks|Preservation of Serum Potassium, The preservation of serum potassium concentrations at ≥ 3.2 meq/L from pre-dosing to post treatment., 2 Weeks |
|
| Sponsor/Collaborators: |
Sponsor: University of California, San Diego | Collaborators: Juvenile Diabetes Research Foundation
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1|PHASE2
|
| Enrollment: |
12
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2023-03-20
|
| Completion Date: |
2026-05-31
|
| Results First Posted: |
|
| Last Update Posted: |
2024-09-19
|
| Locations: |
UC San Diego Altman Clinical & Translational Research Institute, La Jolla, California, 92037, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT05473364
|
