| Trial ID: | L5240 |
| Source ID: | NCT00187564
|
| Associated Drug: |
Controlled-Release Oral Alpha-Lipoic Acid
|
| Title: |
Pilot Study on the Effect of Oral Controlled-Release Alpha-Lipoic Acid on Oxidative Stress in Adolescents With Type 1 Diabetes Mellitus
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus, Type 1
|
| Interventions: |
DRUG: controlled-release oral alpha-lipoic acid
|
| Outcome Measures: |
Primary: 1. protein carbonyl (measurement of oxidized protein)|2. Thiobarbituric Acid Reactive Substances (TBARS) (measurement of oxidized lipid)|3. 8-Oxo-dG/8-Oxo-dA (measurement of oxidized DNA)|4. Trolox equivalent antioxidant capacity (TEAC) (measurement of total antioxidant status) | Secondary: 1. Hb A1c|2. Urine albumin/creatinine ratio
|
| Sponsor/Collaborators: |
Sponsor: University of California, San Francisco
|
| Gender: |
ALL
|
| Age: |
CHILD, ADULT
|
| Phases: |
|
| Enrollment: |
40
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
|
| Start Date: |
2004-08
|
| Completion Date: |
2005-10
|
| Results First Posted: |
|
| Last Update Posted: |
2008-05-06
|
| Locations: |
UCSF Division of Pediatric Endocrinology, San Francisco, California, 94143-0434, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT00187564
|
