Clinical Trial Details
| Trial ID: | L5563 |
| Source ID: | NCT02745470 |
| Associated Drug: | Lixisenatide |
| Title: | Effects of a GLP-1 Receptor Agonist on Functional Activation and Connectivity of the Brain |
| Acronym: | |
| Status: | COMPLETED |
| Study Results: | NO |
| Results: | |
| Conditions: | Diabetes Mellitus |
| Interventions: | DRUG: Lixisenatide|OTHER: Placebo |
| Outcome Measures: | Primary: Difference of BOLD (Blood oxygenation level-dependent) signal in hypothalamus, 10min (40 min after injection)|Whole brain connectivity, 20min (50 min after injection) | Secondary: appetite change, Visual analoge scale-questionnaire consisting of 8 questions (Flint, Raben, Blundell, \& Astrup, 2000), -30min, 45min(after fMRI), 70min(after buffet)|mood change, Visual analoge scale-questionnaire consisting of 16 questions (Boggieo et al., 2008), -30min, 45min(after fMRI), 70min(after buffet)|intake of food in the buffet, It will be provided quantified juice and milk , boiled eggs, bread , bananas and chocolate bars. Participants may eat freely for 20 minutes. Then measure the intake of participants. Compares whether the difference in food intake pattern ., 50min |
| Sponsor/Collaborators: | Sponsor: Seoul National University Hospital | Collaborators: Seoul National University |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | |
| Enrollment: | 30 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE |
| Start Date: | 2016-02 |
| Completion Date: | 2016-12 |
| Results First Posted: | |
| Last Update Posted: | 2017-11-29 |
| Locations: | Seoul National University Hospital, Seoul, 110-744, Korea, Republic of |
| URL: | https://clinicaltrials.gov/show/NCT02745470 |
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