| Outcome Measures: |
Primary: AUC0-last,sema,1mg: Area under the semaglutide concentration time curve from time 0 until last quantifiable measurement after one dose of s.c. semaglutide 1 mg administration following a 6-week dose escalation period, hours\*nmol/L, 0-840 hours after one dose of s.c. semaglutide 1 mg|Cmax,sema,1mg: Maximum observed semaglutide concentration after one dose of s.c. semaglutide 1 mg administration following a 6-week dose escalation period, nmol/L, 0-840 hours after one dose of s.c. semaglutide 1 mg | Secondary: AUC0-168h,sema,0.25mg,SS: Area under the semaglutide concentration time curve from time 0 until 168 hours at steady state after the last dose of s.c. semaglutide 0.25 mg administration, hours\*nmol/L, 0-168 hours after the last dose of s.c. semaglutide 0.25 mg|Cmax,sema,0.25mg,SS: Maximum observed semaglutide concentration at steady state after the last dose of s.c. semaglutide 0.25 mg administration, nmol/L, 0-168 hours after the last dose of s.c. semaglutide 0.25 mg|AUC0-∞,sema,1mg: Area under the semaglutide concentration time curve from time 0 until infinity after one dose of s.c. semaglutide 1 mg administration following a 6-week dose escalation period, hours\*nmol/L, 0-840 hours after one dose of s.c. semaglutide 1 mg|tmax,sema,1mg: Time of maximum observed semaglutide concentration after one dose of s.c. semaglutide 1 mg administration following a 6-week dose escalation period, hours, 0-840 hours after one dose of s.c. semaglutide 1 mg|tmax,sema,0.25mg,SS: Time of maximum observed semaglutide concentration at steady state after the last dose of s.c. semaglutide 0.25 mg administration, hours, 0-168 hours after the last dose of s.c. semaglutide 0.25 mg|t½,sema,1mg: terminal elimination half-life of semaglutide after one dose of s.c. semaglutide 1 mg administration following a 6-week dose escalation period, hours, 0-840 hours after one dose of s.c. semaglutide 1 mg
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