| Outcome Measures: |
Primary: Patients treated with pioglitazone, together with conventional treatment for COVID-19 infection, who during their admission evolve towards the need to receive support with mechanical ventilation, enter the ICU and / or die., Number of patients receive pioglitazone treatment during their hospital stay who receive support with mechanical ventilation, enter the ICU and / or die., Through hospitalization period, an average of 10-20 days until hospital discharge | Secondary: Incidence of pioglitazone treatment-Emergent Adverse Events in patients with DM2 and symptomatic SARS-CoV-2 infection., Proportion of patients who develop heart failure or adverse reaction associated with treatment., Everyday through hospitalization period, an average of 10-20 days until hospital discharge|Biomarker analysis: systemic inflammation parameters during the administration of pioglitazone treatment., Changes in this inflammation parameter: C-reactive protein (in mg/dl), Each 48 hours through hospitalization period, an average of 10-20 days until hospital discharge|Biomarker analysis: systemic inflammation parameters during the administration of pioglitazone treatment., Changes in this inflammation parameter: D-dimer (in μg/mL), Each 48 hours through hospitalization period, an average of 10-20 days until hospital discharge|Biomarker analysis: systemic inflammation parameters during the administration of pioglitazone treatment., Changes in this inflammation parameter: ferritin (in ng/mL), Each 48 hours through hospitalization period, an average of 10-20 days until hospital discharge|Biomarker analysis: systemic inflammation parameters during the administration of pioglitazone treatment., Changes in this inflammation parameter: creatine kinase (CK) (in mg/dL), Each 48 hours through hospitalization period, an average of 10-20 days until hospital discharge|Biomarker analysis: systemic inflammation parameters during the administration of pioglitazone treatment., Changes in this inflammation parameter: number of lymphocytes (in μL), Each 48 hours through hospitalization period, an average of 10-20 days until hospital discharge
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