| Trial ID: | L5799 |
| Source ID: | NCT00943059
|
| Associated Drug: |
Acipimox
|
| Title: |
Cross-over Study on Effect of Lipid Lowering by Acipimox on Cardiac and Skeletal Muscle Mitochondrial Function
|
| Acronym: |
ACP
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus, Type 2|Cardiomyopathy, Dilated
|
| Interventions: |
DRUG: Acipimox|DRUG: Cellulosum Mycrocryst
|
| Outcome Measures: |
Primary: changes in mitochondrial function, 2 weeks|changes in cardiac function, 2 weeks|lipid accumulation in ectopic tissue (cardiac and skeletal muscle), 2 weeks | Secondary: insulin sensitivity, 2 weeks|oxidative stress markers, 2 weeks
|
| Sponsor/Collaborators: |
Sponsor: Maastricht University Medical Center | Collaborators: Center for Translational Molecular Medicine
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
31
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2010-03
|
| Completion Date: |
2012-12
|
| Results First Posted: |
|
| Last Update Posted: |
2013-05-14
|
| Locations: |
Maastricht University Medical Centre, Maastricht, 6200MD, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT00943059
|
