| Trial ID: | L5801 |
| Source ID: | NCT00845559
|
| Associated Drug: |
Exenatide
|
| Title: |
The Effects of Exenatide on Post-Meal Sugar Peaks and Vascular Health in Obese/Pre-Diabetic Young Adults
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| Acronym: |
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| Status: |
WITHDRAWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Obesity|Insulin Resistance|Impaired Glucose Tolerance|Cardiovascular Disease
|
| Interventions: |
DRUG: Exenatide
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| Outcome Measures: |
Primary: Whether treatment with exenatide attenuates post-prandial glycemic excursions as assessed by oral glucose tolerance testing (OGTT) and continuous monitoring system (CGMS) technology., OGTT (Pre- and post-intervention), CGMS (Pre-intervention, 2-months and post-intervention) | Secondary: Cardiovascular risk parameters will be assessed via flow mediated vasodilation, peripheral arterial tonometry, a self-paced step test and biochemical markers of vascular health., Pre- (baseline) and post- (4-months) intervention|Change in body mass index (BMI)., Pre-intervention, 2-month and post-intervention.
|
| Sponsor/Collaborators: |
Sponsor: Yale University | Collaborators: Amylin Pharmaceuticals, LLC.
|
| Gender: |
ALL
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| Age: |
CHILD, ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
0
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2008-08
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| Completion Date: |
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| Results First Posted: |
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| Last Update Posted: |
2012-12-11
|
| Locations: |
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| URL: |
https://clinicaltrials.gov/show/NCT00845559
|
