| Trial ID: | L0599 |
| Source ID: | NCT02753426
|
| Associated Drug: |
Doxycycline
|
| Title: |
A Trial of Doxycycline in Renal Disease
|
| Acronym: |
ADORE
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Chronic Kidney Disease|Cardiorenal Syndrome
|
| Interventions: |
DRUG: Doxycycline|DRUG: Placebo (for Doxycycline)
|
| Outcome Measures: |
Primary: Serum markers of fibrosis, Serum collagen type III amino-terminal propeptide (PIIINP), soluble suppression of tumorigenicity 2 (ST2), 3 months|Urinary markers of fibrosis, Urinary PIIINP, Urinary alpha-1 macroglobulin (A1M), 3 months | Secondary: Adverse effects, Nausea, rash, 3 months
|
| Sponsor/Collaborators: |
Sponsor: University of California, San Francisco
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
11
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
|
| Start Date: |
2016-04
|
| Completion Date: |
2018-01
|
| Results First Posted: |
|
| Last Update Posted: |
2020-02-06
|
| Locations: |
Zuckerberg San Francisco General Hospital, San Francisco, California, 94110, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT02753426
|
