| Outcome Measures: |
Primary: Blood Pressure change, Baseline,4 weeks,8 weeks,12 weeks,16 weeks,20 weeks,up to 24 weeks|Lipid profile (triglyceride, total cholesterol, LDL-c; HDL-c; mmol/L) change, Baseline,4 weeks,8 weeks,12 weeks,16 weeks,20 weeks,up to 24 weeks | Secondary: 24-hours mean blood pressure; incidence of clinical hypertension; Blood pressure variability, Heart rate variability., Baselineļ¼12 weeks,up to 24 weeks|Hemodynamics parameters, including pulse wave velocity(PWV), Baseline,4 weeks,8 weeks,12 weeks,16 weeks,20 weeks,up to 24 weeks|24-hours urine sodium and microalbumin, Baseline,4 weeks,8 weeks,12 weeks,16 weeks,20 weeks,up to 24 weeks|Carotid intima-media thickness(IMT,mm), Baselineļ¼12 weeks,up to 24 weeks|Obesity parameters, including waist circumference (WC,cm) and body mass index(BMI, kg/m2), Baseline,4 weeks,8 weeks,12 weeks,16 weeks,20 weeks,up to 24 weeks|Insulin resistance assessed by fasting serum insulin and HOMA-IR, and control rate of diabetes., Baseline,4 weeks,8 weeks,12 weeks,16 weeks,20 weeks,up to 24 weeks
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