| Trial ID: | L6189 |
| Source ID: | NCT05010356
|
| Associated Drug: |
Insulin
|
| Title: |
Insulin Sensitivity After Breast Cancer
|
| Acronym: |
|
| Status: |
RECRUITING
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Insulin Sensitivity/Resistance|Breast Cancer|Survivorship|Metabolic Disturbance
|
| Interventions: |
DRUG: Insulin
|
| Outcome Measures: |
Primary: Insulin sensitivity status, Glucose infusion rate during the hyperinsulinemic euglycemic clamp to ascertain the insulin sensitivity, 2 years|Hepatic glucose production, Measurements from the Hyperinsulinemic Euglycemic Clamp will be used to assess insulin effects on hepatic glucose production, 2 years | Secondary: Proteomic changes in skeletal muscle, Skeletal muscle biopsies from the vastus lateralis muscle will be analysez using mass spectometry to determine proteomic chances in response to breast cancer in skeletal muscle, 4 years|Insulin signaling, Intracellular insulin signaling will be determined using western blotting technique, 4 years
|
| Sponsor/Collaborators: |
Sponsor: University of Copenhagen
|
| Gender: |
FEMALE
|
| Age: |
ADULT
|
| Phases: |
|
| Enrollment: |
24
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2021-08
|
| Completion Date: |
2026-09
|
| Results First Posted: |
|
| Last Update Posted: |
2021-08-18
|
| Locations: |
University of Copenhagen, Copenhagen, DK, 2100, Denmark
|
| URL: |
https://clinicaltrials.gov/show/NCT05010356
|
