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Clinical Trial Details

Trial ID: L6525
Source ID: NCT06603571
Associated Drug: Ly3841136
Title: A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Acronym:
Status: RECRUITING
Study Results: NO
Results:
Conditions: Obesity|Overweight
Interventions: DRUG: LY3841136|DRUG: Tirzepatide|DRUG: Placebo
Outcome Measures: Primary: Percent Change from Baseline in Body Weight, Baseline, Week 48 | Secondary: Change from Baseline in Body Weight, Baseline, Week 48|Percentage of Participants Who Achieve ≥5% Body Weight Reduction, Week 48|Percentage of Participants Who Achieve ≥10% Body Weight Reduction, Week 48|Change from baseline in Hemoglobin A1c (HbA1c), Baseline, Week 48|Pharmacokinetics (PK): Area Under the Curve (AUC) of LY3841136, Baseline, Week 48|PK: Maximum Concentration (Cmax) of LY3841136, Baseline, Week 48
Sponsor/Collaborators: Sponsor: Eli Lilly and Company
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE2
Enrollment: 350
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Start Date: 2024-09-20
Completion Date: 2026-08
Results First Posted:
Last Update Posted: 2025-02-27
Locations: The Institute for Liver Health II dba Arizona Clinical Trials - Mesa, Chandler, Arizona, 85225, United States|HOPE Research Institute, Phoenix, Arizona, 85032, United States|Headlands Research - Scottsdale, Scottsdale, Arizona, 85260, United States|The Institute for Liver Health II dba Arizona Liver Health-Tucson, Tucson, Arizona, 85712, United States|NorCal Medical Research, Inc, Greenbrae, California, 94904, United States|Velocity Clinical Research, Huntington Park, Huntington Park, California, 90255, United States|Peninsula Research Associates, Rolling Hills Estates, California, 90274, United States|Diablo Clinical Research, Inc., Walnut Creek, California, 94598, United States|Stamford Therapeutics Consortium, Stamford, Connecticut, 06905, United States|Northeast Research Institute (NERI), Fleming Island, Florida, 32003, United States|Indago Research & Health Center, Inc, Hialeah, Florida, 33012, United States|New Horizon Research Center, Miami, Florida, 33165, United States|Suncoast Clinical Research, Inc., New Port Richey, Florida, 34652, United States|Charter Research - Winter Park, Orlando, Florida, 32803, United States|Charter Research - Lady Lake, The Villages, Florida, 32162, United States|Medical Research Partners, Ammon, Idaho, 83406, United States|Great Lakes Clinical Trials - Andersonville, Chicago, Illinois, 60640, United States|Great Lakes Clinical Trials - Ravenswood, Chicago, Illinois, 60640, United States|NorthShore University Health System, Skokie, Illinois, 60077, United States|Iowa Diabetes and Endocrinology Research Center, West Des Moines, Iowa, 50266, United States|Cotton O'Neil Diabetes & Endocrinology, Topeka, Kansas, 66606, United States|Knownwell, Needham, Massachusetts, 02492, United States|Lucida Clinical Trials, New Bedford, Massachusetts, 02740, United States|Headlands Research - Detroit, Southfield, Michigan, 48034, United States|Arcturus Healthcare , PLC, Troy Internal Medicine Research Division, Troy, Michigan, 48098, United States|StudyMetrix Research, Saint Peters, Missouri, 63303, United States|Clinvest Headlands Llc, Springfield, Missouri, 65807, United States|Las Vegas Medical Research, Las Vegas, Nevada, 89128, United States|Dent Neurologic Institute, Amherst, New York, 14226, United States|Velocity Clinical Research, Syracuse, East Syracuse, New York, 13057, United States|North Suffolk Neurology, Port Jefferson Station, New York, 11776, United States|Rochester Clinical Research, LLC, Rochester, New York, 14609, United States|Medication Management, Greensboro, North Carolina, 27405, United States|Monroe Biomedical Research, Monroe, North Carolina, 28112, United States|Lucas Research, Inc, Morehead City, North Carolina, 28557, United States|Lucas Research, Inc., New Bern, North Carolina, 28562, United States|CTI Clinical Research Center, Cincinnati, Ohio, 45212, United States|Tribe Clinical Research, LLC, Greenville, South Carolina, 29607, United States|Quality Medical Research, Nashville, Tennessee, 37211, United States|IMA Clinical Research Austin, Austin, Texas, 78745, United States|Velocity Clinical Research, Dallas, Dallas, Texas, 75230, United States|FutureSearch Trials of Dallas, Dallas, Texas, 75251, United States|PlanIt Research, PLLC, Houston, Texas, 77079, United States|Tekton Research - Fredericksburg Road, San Antonio, Texas, 78229, United States|Endeavor Clinical Trials, San Antonio, Texas, 78240, United States|Texas Valley Clinical Research, Weslaco, Texas, 78596, United States|Spectrum Medical, Inc., Danville, Virginia, 24541, United States|Central Washington Health Services Association d/b/a Confluence Health, Wenatchee, Washington, 98801, United States|Centro Médico Viamonte, Buenos Aires, Ciudad Autónoma De Buenos Aires, C1120AAC, Argentina|Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada, Ciudad Autonoma de Buenos Aires, Ciudad Autónoma De Buenos Aires, C1425AGC, Argentina|Centro de Investigaciones Metabólicas (CINME), Ciudad Autónoma de Buenos Aires, C1056ABI, Argentina
URL: https://clinicaltrials.gov/show/NCT06603571

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress