| Trial ID: | L6577 |
| Source ID: | NCT02502071
|
| Associated Drug: |
Sodium Bicarbonate
|
| Title: |
Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetes
|
| Acronym: |
Alk-UA
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT02502071/results
|
| Conditions: |
Type 1 Diabetes|Diabetic Nephropathy|Diabetic Kidney Disease
|
| Interventions: |
DRUG: sodium bicarbonate
|
| Outcome Measures: |
Primary: Change in Urine Uric Acid Concentration (Increased Solubility) by Assay, Urine uric acid were evaluated using a QuantiChrom UA kit assay (DIUA-250) with quantitative colorimetric UA determination at 590 nm (BioAssay System, California, USA)., Day 1 (pre-therapy) and Day 2 (post-therapy)|Change in Number of Participants With Urine Uric Acid Precipitation by Polarized Microscopy, Urine uric acid crystals were identified by polarized microscopy (Polarized light imaging Zeiss Axiovert 135; 0.3NA objective), and pictures were captured from each urine sample. UA crystals were defined dichotomously as being present or absent., Day 1 (pre-therapy) and Day 2 (post-therapy) |
|
| Sponsor/Collaborators: |
Sponsor: University of Colorado, Denver
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
45
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2017-01
|
| Completion Date: |
2017-08
|
| Results First Posted: |
2018-11-20
|
| Last Update Posted: |
2022-01-24
|
| Locations: |
Barbara Davis Center for Diabetes, Aurora, Colorado, 80045, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT02502071
|
