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Clinical Trial Details

Trial ID: L6580
Source ID: NCT06613893
Associated Drug: Tiva
Title: Effect of Inhalational Anesthesia Versus Total Intravenous Anesthesia on Blood Glucose in Type 2 Diabetes Patients
Acronym:
Status: NOT_YET_RECRUITING
Study Results: NO
Results:
Conditions: Type 2 Diabetes Mellitus (T2DM)|Thoracic Surgery
Interventions: DRUG: TIVA|DRUG: Inhalational anesthesia
Outcome Measures: Primary: Blood glucose levels in milligrams per decilitre (mg/dl) at different time points, Blood glucose levels in milligrams per deciliter at different time points: preoperative (T0), post-intubation (T1), 1st , 2nd and 3rd hour after the start of the operation (T3, T4 and T5, respectively), 1st hour after the operation (T6) , 2nd hour after the operation (T7), 1st and 2nd day after the operation (T8, T9), Immediate preoperative till 48 hours after recovery from anesthesia | Secondary: Serum insulin level in picomoles per litre (pmol/l), serum insulin level (pmol/l) 30 min before and 30 min after surgery, 30 min before induction of anesthesia and 30 min after surgery and recovery from anesthesia|Serum cortisol level in micrograms per decilitre (mcg/dl), serum cortisol level (mcg/dl) 30 min before and 30 min after surgery, 30 min before induction of anesthesia and 30 min after surgery and recovery from anesthesia|The incidence of postoperative complications, The complications that will be tested Acute coronary syndrome. Stroke. acute kidney injury. stress gastric ulcer. surgical site infection. Hypoglycaemia (blood glucose level below 70 mg/dL). Hyperglycemia (fasting blood glucose level greater than 125mg/dL while 2 hours postprandial greater than 200 mg/dL). Postoperative nausea and vomiting . postoperative pulmonary complications including atelectasis, pneumonia and respiratory failure, The complications will be assessed on the first, third and seveth post-operative day
Sponsor/Collaborators: Sponsor: Ain Shams University
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases:
Enrollment: 42
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Start Date: 2024-12-01
Completion Date: 2026-02-28
Results First Posted:
Last Update Posted: 2024-11-29
Locations: Ain Shams University, Cairo, Egypt
URL: https://clinicaltrials.gov/show/NCT06613893