| Trial ID: | L6583 |
| Source ID: | NCT01677611
|
| Associated Drug: |
Trans-Resveratrol Extract From Polygonum Cuspidatum
|
| Title: |
Effects of Resveratrol in Patients With Type 2 Diabetes
|
| Acronym: |
RED
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: Trans-resveratrol extract from Polygonum Cuspidatum|DRUG: Placebo
|
| Outcome Measures: |
Primary: Skeletal muscle sirtuin 1 (SIRT1) expression, 3 months | Secondary: Skeletal muscle 5'-AMP-activated protein kinase (AMPK) expression, 3 months|Skeletal muscle phosphorylated-AMPK-Thr172 (p-AMPK) expression, 3 months|Skeletal muscle glucose transporter type 4 (GLUT 4) expression, 3 months|Glycated hemoglobin (HbA1c), 3 months|Body weight, 3 months|Insulin sensitivity, 3 months|Lipid profile, 3 months|Energy expenditure, 3 months|Physical activity level, 3 months|Abdominal adipose tissue distribution, 3 months|Skeletal muscle fibre type composition, 3 months|Renal function, Serum creatinine, 3 months|Liver function, Transaminases, 3 months
|
| Sponsor/Collaborators: |
Sponsor: Khoo Teck Puat Hospital | Collaborators: National Medical Research Council (NMRC), Singapore
|
| Gender: |
MALE
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
10
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2008-12
|
| Completion Date: |
2012-03
|
| Results First Posted: |
|
| Last Update Posted: |
2012-09-03
|
| Locations: |
Alexandra Health, Khoo Teck Puat Hospital, Singapore, 768828, Singapore
|
| URL: |
https://clinicaltrials.gov/show/NCT01677611
|
