| Outcome Measures: |
Primary: Neurocognitive performance- change in global cognitive scores on a standard neuropsychological profile, 6 months|Neurocognitive performance- change in domain averages on a standard neuropsychological profile, 6 months | Secondary: Change from baseline high sensitivity C-reactive protein, 3 and 6 months|Change from baseline d-dimer, 3 and 6 months|Change from baseline Interleukin 6, 3 and 6 months|Change from baseline plasma soluble cluster of differentiation 14 (CD14), 3 and 6 months|Change from baseline BMI, 3 and 6 months|Change from baseline weight, 3 and 6 months|Change from baseline waist circumference, 3 and 6 months|Change from baseline blood pressure, 3 and 6 months|Change from baseline serum triglycerides, 3 and 6 months|Change from baseline insulin resistance by homeostasis model assessment (HOMA-IR) in subjects not on insulin, 3 and 6 months|Change from baseline liver enzymes aspartate aminotransferase and alanine aminotransferase, 3 and 6 months|Change from baseline Hemoglobin A1c, 3 and 6 months|Change from baseline fructosamine, 3 and 6 months|Number of Adverse events, 3 and 6 months|Number of subjects with Adverse events, 3 and 6 months|Change from baseline serum LDL, 3 and 6 months
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