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Clinical Trial Details

Trial ID: L6811
Source ID: NCT05037045
Associated Drug: Glp-1 Receptor Agonist
Title: Effect of Gene Polymorphisms on GLP-1 Receptor Agonists Response in Patients With T2DM
Acronym:
Status: COMPLETED
Study Results: NO
Results:
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: GLP-1 receptor agonist
Outcome Measures: Primary: Change from baseline HbA1c at 1 month, In order to observe the change from baseline HbA1c at 1 month after GLP-1 RA treatment, 1 month after GLP-1 RA treatment|Change from baseline FPG at 1 month, In order to observe the change from baseline FPG at 1 month after GLP-1 RA treatment, 1 month after GLP-1 RA treatment|Change from baseline PPG at 1 month, In order to observe the change from baseline PPG at 1 month after GLP-1 RA treatment, 1 month after GLP-1 RA treatment|Change from baseline serum lipids at 1 month, In order to observe the change from baseline serum lipids at 1 month after GLP-1 RA treatment, 1 month after GLP-1 RA treatment|Change from baseline HbA1c at 3 month, In order to observe the change from baseline HbA1c at 3 month after GLP-1 RA treatment, 3 month after GLP-1 RA treatment|Change from baseline FPG at 3 month, In order to observe the change from baseline FPG at 3 month after GLP-1 RA treatment, 3 month after GLP-1 RA treatment|Change from baseline PPG at 3 month, In order to observe the change from baseline PPG at 3 month after GLP-1 RA treatment, 3 month after GLP-1 RA treatment|Change from baseline serum lipids at 3 month, In order to observe the change from baseline serum lipids at 3 month after GLP-1 RA treatment, 3 month after GLP-1 RA treatment|Change from baseline HbA1c at 6 month, In order to observe the change from baseline HbA1c at 6 month after GLP-1 RA treatment, 6 month after GLP-1 RA treatment|Change from baseline FPG at 6 month, In order to observe the change from baseline FPG at 6 month after GLP-1 RA treatment, 6 month after GLP-1 RA treatment|Change from baseline PPG at 6 month, In order to observe the change from baseline PPG at 6 month after GLP-1 RA treatment, 6 month after GLP-1 RA treatment|Change from baseline serum lipids at 6 month, In order to observe the change from baseline serum lipids at 6 month after GLP-1 RA treatment, 6 month after GLP-1 RA treatment | Secondary: incidence and severity of possible adverse reaction within 1 month after GLP-1 RA treatment, To evaluate the incidence and severity of possible adverse reaction within 1 month after GLP-1 RA treatment, including gastrointestinal reaction and hypoglycemia, 1 month after GLP-1 RA treatment|incidence and severity of possible adverse reaction within 3 month after GLP-1 RA treatment, To evaluate the incidence and severity of possible adverse reaction within 3 month after GLP-1 RA treatment, including gastrointestinal reaction and hypoglycemia, 3 month after GLP-1 RA treatment|incidence and severity of possible adverse reaction within 6 month after GLP-1 RA treatment, To evaluate the incidence and severity of possible adverse reaction within 6 month after GLP-1 RA treatment, including gastrointestinal reaction and hypoglycemia, 6 month after GLP-1 RA treatment
Sponsor/Collaborators: Sponsor: The Affiliated Hospital of Xuzhou Medical University
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases:
Enrollment: 338
Study Type: INTERVENTIONAL
Study Designs: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2019-01-10
Completion Date: 2024-01-02
Results First Posted:
Last Update Posted: 2024-11-12
Locations: Department of Endocrinology, Xuzhou, Jiangsu, China
URL: https://clinicaltrials.gov/show/NCT05037045