| Outcome Measures: |
Primary: Adverse events, laboratory variables, physical examination, cardiac evaluation, hypoglycemic events, electrocardiogram, vital signs (blood pressure and pulse), body weight | Secondary: Effect of tesaglitazar versus glibenclamide, with or without other oral anti-diabetic drugs on|Time to treatment failure|Changes in glycemic variables: glycosylated hemoglobin A1c and fasting plasma glucose (FPG)|Responder rates and proportion of patients who reach pre-specified target levels for glycosylated hemoglobin A1c and FPG|Markers of insulin resistance by assessment of insulin homeostasis assessment model|Preventing beta-cell function by assessment of changes in the ratios proinsulin/insulin and C-peptide/FPG|Changes in lipid variables (triglyceride, total cholesterol, high-density lipoprotein cholesterol [HDL-C], non-HDL-C, low-density lipoprotein cholesterol, low-density lipoprotein cholesterol/HDL-C, apolipoprotein [Apo] B, ApoA-1, ApoB/ApoA-1|Responder rates and proportion of patients who reach pre-specified target levels for triglyceride and HDL-C|Inflammatory and coagulability markers by assessment of C-reactive protein, fibrinogen, tumor necrosis factor-alpha, and intracellular adhesion molecule-1|Urinary albumin excretion|Central obesity (waist circumference, hip circumference and waist/hip ratio)
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| Locations: |
Research Site, Hasselt, Belgium|Research Site, Liege, Belgium|Research Site, Sint-Gillis-Waas, Belgium|Research Site, Steenokkerzeel, Belgium|Research Site, Shatin, Hong Kong|Research Site, Balatonfured, Hungary|Research Site, Budapest, Hungary|Research Site, Kaposvar, Hungary|Research Site, Kecskemet, Hungary|Research Site, Székesfehérvár, Hungary|Research Site, Gubbio, Italy|Research Site, Milano, Italy|Research Site, Perugia, Italy|Research Site, Piacenza, Italy|Research Site, Reggio Emilia, Italy|Research Site, Udine, Italy|Research Site, Kubang Kerian, Kelantan, Malaysia|Research Site, Kuala Lumpur, Malaysia|Research Site, Makati City, Philippines|Research Site, Manila, Philippines|Research Site, Pasig City, Philippines|Research Site, Kraków, Poland|Research Site, Lublin, Poland|Research Site, Plock, Poland|Research Site, Torun, Poland|Research Site, Tychy, Poland|Research Site, Warszawa, Poland|Research Site, £ód?, Poland|Research Site, Banská Bystrica, Slovakia|Research Site, Bratislava, Slovakia|Research Site, Ilava, Slovakia|Research Site, Kosice, Slovakia|Research Site, Kysucke Nove Mesto, Slovakia|Research Site, Lubochna, Slovakia|Research Site, Lucenec, Slovakia|Research Site, Nitra, Slovakia|Research Site, Presov, Slovakia|Research Site, Trnava, Slovakia|Research Site, Johannesburg, Gauteng, South Africa|Research Site, Cape Town, South Africa|Research Site, Durban, South Africa|Research Site, Bangkok, Thailand
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