| Trial ID: | L7063 |
| Source ID: | NCT01056497
|
| Associated Drug: |
Alpha Lipoic Acid
|
| Title: |
The Effect of A-lipoic Acid (ALA) on Fatty Acid-induced Impairment of Glucose-stimulated Insulin Secretion
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes|Prediabetes
|
| Interventions: |
DRUG: alpha lipoic acid
|
| Outcome Measures: |
Primary: insulin secretion and insulin sensitivity To determine whether ALA ameliorates or prevents impairment of insulin secretion and insulin sensi, 6 months | Secondary: To determine the role of oxidative stress and inflammation in the pathogenesis of lipotoxicity, 6 months
|
| Sponsor/Collaborators: |
Sponsor: University Health Network, Toronto | Collaborators: Canadian Diabetes Association
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
15
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2010-02
|
| Completion Date: |
2011-06
|
| Results First Posted: |
|
| Last Update Posted: |
2012-10-02
|
| Locations: |
Toronto General Hospital, Toronto, Ontario, M5G 2C4, Canada
|
| URL: |
https://clinicaltrials.gov/show/NCT01056497
|
