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Clinical Trial Details

Trial ID: L7088
Source ID: NCT01952145
Associated Drug: Insulin Degludec/Liraglutide
Title: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus
Acronym: DUAL™ V
Status: COMPLETED
Study Results: YES
Results: https://ClinicalTrials.gov/show/NCT01952145/results
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: insulin glargine
Outcome Measures: Primary: Change From Baseline in HbA1c (Glycosylated Haemoglobin), Change from baseline in HbA1c after 26 weeks of treatment, Week 0, week 26 | Secondary: Change From Baseline in Body Weight, Change from baseline in body weight after 26 weeks of treatment, Week 0, week 26|Number of Treatment Emergent Confirmed Hypoglycaemic Episodes, Confirmed hypoglycaemic episodes were defined as either: Severe (i.e., an episode requiring assistance of another person to actively administer carbohydrate, glucagon, or other resuscitative actions) or an episode biochemically confirmed by a plasma glucose value of \<3.1 mmol/L (56 mg/dL), with or without symptoms consistent with hypoglycaemia., During 26 weeks of treatment
Sponsor/Collaborators: Sponsor: Novo Nordisk A/S
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE3
Enrollment: 557
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2013-09-20
Completion Date: 2014-11-04
Results First Posted: 2017-01-20
Last Update Posted: 2019-01-03
Locations: Novo Nordisk Investigational Site, Fresno, California, 93720, United States|Novo Nordisk Investigational Site, Los Alamitos, California, 90720, United States|Novo Nordisk Investigational Site, Palm Springs, California, 92262, United States|Novo Nordisk Investigational Site, San Diego, California, 92111, United States|Novo Nordisk Investigational Site, Colorado Springs, Colorado, 80906, United States|Novo Nordisk Investigational Site, Colorado Springs, Colorado, 80909, United States|Novo Nordisk Investigational Site, Bradenton, Florida, 34201, United States|Novo Nordisk Investigational Site, Fort Lauderdale, Florida, 33316, United States|Novo Nordisk Investigational Site, Miami, Florida, 33165, United States|Novo Nordisk Investigational Site, Pembroke Pines, Florida, 33027, United States|Novo Nordisk Investigational Site, Tampa, Florida, 33603, United States|Novo Nordisk Investigational Site, Gurnee, Illinois, 60031, United States|Novo Nordisk Investigational Site, Evansville, Indiana, 47725, United States|Novo Nordisk Investigational Site, Michigan City, Indiana, 46360, United States|Novo Nordisk Investigational Site, Lexington, Kentucky, 40503, United States|Novo Nordisk Investigational Site, Louisville, Kentucky, 40213, United States|Novo Nordisk Investigational Site, Slidell, Louisiana, 70461-4231, United States|Novo Nordisk Investigational Site, Saint Charles, Missouri, 63303, United States|Novo Nordisk Investigational Site, Wilmington, North Carolina, 28401, United States|Novo Nordisk Investigational Site, Franklin, Ohio, 45005, United States|Novo Nordisk Investigational Site, Oklahoma City, Oklahoma, 73103, United States|Novo Nordisk Investigational Site, Oklahoma City, Oklahoma, 73104, United States|Novo Nordisk Investigational Site, Altoona, Pennsylvania, 16602, United States|Novo Nordisk Investigational Site, Philadelphia, Pennsylvania, 19140, United States|Novo Nordisk Investigational Site, Collierville, Tennessee, 38017, United States|Novo Nordisk Investigational Site, Kingsport, Tennessee, 37660, United States|Novo Nordisk Investigational Site, Dallas, Texas, 75390-9302, United States|Novo Nordisk Investigational Site, San Antonio, Texas, 78224, United States|Novo Nordisk Investigational Site, West Jordan, Utah, 84088-8871, United States|Novo Nordisk Investigational Site, Renton, Washington, 98057, United States|Novo Nordisk Investigational Site, Spokane, Washington, 99218, United States|Novo Nordisk Investigational Site, Buenos Aires, B1704ETD, Argentina|Novo Nordisk Investigational Site, Capital Federal, C1056ABJ, Argentina|Novo Nordisk Investigational Site, Corrientes, 3400, Argentina|Novo Nordisk Investigational Site, Salta, 4400, Argentina|Novo Nordisk Investigational Site, Zarate, B2800DGH, Argentina|Novo Nordisk Investigational Site, Blacktown, New South Wales, 2148, Australia|Novo Nordisk Investigational Site, Wollongong, New South Wales, 2500, Australia|Novo Nordisk Investigational Site, Herston, Queensland, 4029, Australia|Novo Nordisk Investigational Site, Ipswich, Queensland, 4305, Australia|Novo Nordisk Investigational Site, Robina, Queensland, 4226, Australia|Novo Nordisk Investigational Site, East Ringwood, Victoria, 3135, Australia|Novo Nordisk Investigational Site, Athens, GR-11527, Greece|Novo Nordisk Investigational Site, Athens, GR-14233, Greece|Novo Nordisk Investigational Site, Ioannina, 45500, Greece|Novo Nordisk Investigational Site, Larissa, GR-41110, Greece|Novo Nordisk Investigational Site, Thessaloniki, GR-54642, Greece|Novo Nordisk Investigational Site, Thessaloniki, GR-56403, Greece|Novo Nordisk Investigational Site, Thessaloniki, GR-57001, Greece|Novo Nordisk Investigational Site, Budapest, H-1134, Hungary|Novo Nordisk Investigational Site, Eger, 3300, Hungary|Novo Nordisk Investigational Site, Gyor, 9024, Hungary|Novo Nordisk Investigational Site, Gyula, 5700, Hungary|Novo Nordisk Investigational Site, Miskolc, 3526, Hungary|Novo Nordisk Investigational Site, Pachuca, Hidalgo, 42084, Mexico|Novo Nordisk Investigational Site, Cuernavaca, Morelos, 62250, Mexico|Novo Nordisk Investigational Site, Mexico City, México, D.F., 03300, Mexico|Novo Nordisk Investigational Site, Durango, 34000, Mexico|Novo Nordisk Investigational Site, Monterrey, 64460, Mexico|Novo Nordisk Investigational Site, Kazan, 420073, Russian Federation|Novo Nordisk Investigational Site, Kirov, 610014, Russian Federation|Novo Nordisk Investigational Site, Moscow, 117036, Russian Federation|Novo Nordisk Investigational Site, Moscow, 123448, Russian Federation|Novo Nordisk Investigational Site, Novosibirsk, 630117, Russian Federation|Novo Nordisk Investigational Site, Saint-Petersburg, 194358, Russian Federation|Novo Nordisk Investigational Site, Saint-Petersburg, 199034, Russian Federation|Novo Nordisk Investigational Site, St. Petersburg, 194354, Russian Federation|Novo Nordisk Investigational Site, Tomsk, 634041, Russian Federation|Novo Nordisk Investigational Site, Tomsk, 634050, Russian Federation|Novo Nordisk Investigational Site, Volgograd, 400131, Russian Federation|Novo Nordisk Investigational Site, Vsevolozhsk, 188643, Russian Federation|Novo Nordisk Investigational Site, Bardejov, 08501, Slovakia|Novo Nordisk Investigational Site, Dolny Kubin, 02601, Slovakia|Novo Nordisk Investigational Site, Kosice, 040 11, Slovakia|Novo Nordisk Investigational Site, Kosice, 04001, Slovakia|Novo Nordisk Investigational Site, Levice, 93401, Slovakia|Novo Nordisk Investigational Site, Lubochna, 03491, Slovakia|Novo Nordisk Investigational Site, Poprad, 05801, Slovakia|Novo Nordisk Investigational Site, Povazska Bystrica, 01701, Slovakia|Novo Nordisk Investigational Site, Prievidza, 97101, Slovakia|Novo Nordisk Investigational Site, Trnava, 91701, Slovakia|Novo Nordisk Investigational Site, Velky Meder, 93201, Slovakia|Novo Nordisk Investigational Site, Midrand, Gauteng, 1685, South Africa|Novo Nordisk Investigational Site, Durban, KwaZulu-Natal, 4450, South Africa|Novo Nordisk Investigational Site, Alberton, 1449, South Africa|Novo Nordisk Investigational Site, Almería, 04001, Spain|Novo Nordisk Investigational Site, Granada, 18012, Spain|Novo Nordisk Investigational Site, Palma de Mallorca, 07014, Spain|Novo Nordisk Investigational Site, Sevilla, 41003, Spain|Novo Nordisk Investigational Site, Sevilla, 41010, Spain|Novo Nordisk Investigational Site, Valencia, 46026, Spain
URL: https://clinicaltrials.gov/show/NCT01952145

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress