| Trial ID: | L7146 |
| Source ID: | NCT01096277
|
| Associated Drug: |
Sitagliptin
|
| Title: |
Vascular Effects of Sitagliptin in Diabetes Mellitus
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Sitagliptin|DRUG: Placebo|OTHER: Control
|
| Outcome Measures: |
Primary: Endothelial function, Effect of sitagliptin on endothelium-dependent vasodilation before and after treatment of patients with type 2 diabetes mellitus with the DPP-4-inhibitor sitagliptin and placebo treatment respectively, Before and after two week treatment | Secondary: Effect on EPCs, Effect of sitagliptin on mobilization, NO-production and in vivo regenerative capacity of human endothelial progenitor cells before and after treatment of patients with type 2 diabetes mellitus with the DPP-4-inhibitor sitagliptin and placebo treatment respectively, Before and after two week treatment
|
| Sponsor/Collaborators: |
Sponsor: Hannover Medical School
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
70
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2010-10
|
| Completion Date: |
2012-12
|
| Results First Posted: |
|
| Last Update Posted: |
2010-03-31
|
| Locations: |
Hannover Medical School, Hannover, 30625, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT01096277
|
