| Outcome Measures: |
Primary: Changes of mean hemoglobin compared to baseline., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups. | Secondary: Proportion of patients with hemoglobin keeping within the target range (the target hemoglobin range is defined as hemoglobin keeping between 100g/L and 120g/L)., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups.|Proportion of patients with hemoglobin fluctuations within ±10g/L compared to baseline., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups.|Mean time of hemoglobin keeping within the target range., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups.|Mean time from baseline to the first dose adjustment., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups.|Changes of hemoglobin compared to baseline at the time of first dose adjustment., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups.|Proportion of patients with dose adjustment., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups.|Proportion of patients requiring blood transfusion., 14 weeks for every two weeks groups, and 16 weeks for every four weeks groups.
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| Locations: |
Beijing Anzhen Hospital,Capital Medical University, Beijing, Beijing, China|The Second Affiliated Hospital Of Chongqing Medical University, Chongqing, Chongqing, China|The First Affiliated Hospital Of Guangzhou Medical University, Guangzhou, Guangdong, China|The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China|The Third Affiliated Hospital of Sun Yat sen University, Guanzhou, Guangdong, China|Renmin Hospital of Wuhan University/Hubei General Hospital, Wuhan, Hubei, China|The Third Xiangya Hospital Of Central South University, Changsha, Hunan, China|Xiangya Hospital Central South University, Changsha, Hunan, China|The First Affiliated Hospital Of Baotou Medical college,Inner Mongolia University Of Science and Technology, Hohhot, Inner Mongol, China|Huai'an Second People's Hospital/The Affiliated Huaian Hospital Of Xuzhou Medical University, Huai'an, Jiangsu, China|Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China|Xi'an Gaoxin Hospital, Xi'an, Shanxi, China|The First Affiliated Hospital Of Chengdu Medical college, Chengdu, Sichuan, 361028, China|Tianjin First Central Hospital, Tianjin, Tianjin, China|Tianjin People's Hospital, Tianjin, Tianjin, China|The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China|Lishui Municipal Central Hospital, Lishui, Zhejiang, China
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